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Description

This is most likely due to the fact that the elevated IGF-I levels that exist in this pathology lead to increased klotho secretion which, in turn, further increases GH secretion

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Additionally, treatment of several cancer types with the enzyme asparaginase, or dietary restriction of asparagine, reduces metastasis but does not alter the growth of primary tumors

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doi:10.1371/journal.pone.0151653 [PubMed] Steenge GR, Verhoef P, Katan MB

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